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Surging New COVID-19 Variant “Nimbus” Causes “Razor Blade Throat”, Hits China and US

A newly identified COVID-19 variant, dubbed “Nimbus” or NB.1.8.1 and colloquially referred to as “razor blade throat” COVID, has captured the attention of health professionals worldwide. Its defining feature is a notably sharp and painful sore throat, a symptom that stands out from the more common respiratory complaints linked to previous strains.

First detected in several countries, including the United Kingdom and India, Nimbus now accounts for roughly 11% of sequenced COVID-19 cases globally, signalling its growing presence beyond isolated pockets.

Scientists emphasise that while mutations in the SARS-CoV-2 virus are expected in its ongoing evolution, not all variants lead to increased danger. The World Health Organisation has classified Nimbus as a “variant under monitoring”, a category indicating that it warrants watchful observation but does not currently represent a significant threat to public health on a global scale.

Early clinical data suggest that Nimbus infections do not cause more severe illness or higher death rates compared to earlier variants. Vaccines authorised for use continue to offer protection, reducing the risk of serious outcomes.

Despite this reassurance, the emergence of Nimbus serves as a reminder of the virus’s capacity to change and adapt. Its distinctive symptom — an intense sore throat described by patients as sharper than usual — has prompted media interest and heightened awareness among clinicians.

In the United States, airport screenings have detected cases of Nimbus in travellers arriving from affected regions, including states such as California, Washington, Virginia and New York. This highlights how interconnected global travel remains a crucial factor in the spread of new variants.

While sore throats are common in respiratory infections, the intensity associated with Nimbus seems notably stronger, warranting further investigation. Experts caution against alarm but stress that recognising shifts in symptom patterns can aid in early identification and management.

Common COVID-19 symptoms—such as fever, cough, chills and loss of taste or smell—persist across variants. The addition of severe sore throat does not alter the overall clinical approach but underscores the virus’s evolving nature.

In Malaysia, it presents an intriguing case in the current COVID-19 landscape. Unlike neighbouring Singapore and Hong Kong, which have recently experienced pronounced surges in COVID-19 infections, Malaysia’s case numbers have remained relatively stable and below alert thresholds throughout May 2025. Health authorities report just over 11,000 cases recorded this year up to 20 May, continuing a steady decline that began early in the year.

Hospital admissions related to COVID-19 have also trended downward. The seven-day average dropped from 45 in late April to 37 by mid-May. This contrasts sharply with Singapore’s 28% rise over the same period, despite similarities in regional proximity and socio-economic factors. Malaysia’s trajectory suggests that effective public health measures and vaccination efforts have played a significant role in curbing transmission.

Nonetheless, Malaysia recently marked its first COVID-19-related death of 2025 during epidemiological week 24. The deceased was a patient with underlying conditions including diabetes and heart disease who had not received the second booster dose of the vaccine.

This case starkly illustrates the continued vulnerability of individuals with comorbidities who remain unprotected or under-protected. It aligns with global findings that such groups face disproportionately higher risks of severe illness and death from COVID-19.

Throughout 2024, Malaysia recorded 57 COVID-19 fatalities, a figure that has sharply fallen to one so far this year. While this decline is encouraging, health officials urge caution as reported infections show signs of modest increase. The pandemic is far from over; vigilance remains paramount.

In terms of healthcare burden, six patients required admission to intensive care units during week 24. All admitted individuals had pre-existing health conditions such as hypertension, diabetes, dyslipidaemia, heart disease or Down syndrome — conditions known to exacerbate COVID-19 severity.

Four patients have since been discharged home, while two remain hospitalised on regular wards. These figures underline that serious outcomes predominantly affect vulnerable populations despite broad improvements in treatment and vaccination coverage.

Vaccination continues to be at the heart of Malaysia’s pandemic response strategy. Authorities recommend additional booster doses for high-risk groups including elderly individuals, people with multiple comorbidities, immunocompromised adolescents, pregnant women and healthcare workers.

Vaccination remains voluntary for adults aged 18 and above but is strongly encouraged following medical consultation tailored to individual risk profiles.

This approach aligns with international guidelines from organisations such as the World Health Organisation and Centres for Disease Control and Prevention. Boosters help counter waning immunity over time and provide enhanced protection against emerging variants like Nimbus and others circulating globally.

The broader Western Pacific region offers important context for Malaysia’s experience. As reported by the WHO in May 2025, dominant variants circulating include JN.1 and B.1.1.529, with positivity rates averaging around 8% across multiple countries.

Despite geographic proximity to Malaysia, Singapore and Hong Kong have endured sharp rises in infections recently — a reminder that local factors such as population density, community behaviour, public health interventions and vaccination coverage can significantly influence outcomes.

Across the Atlantic Ocean, the United States presents a patchwork of COVID-19 trends. According to the CDC’s mid-May estimates, infections are rising or expected to rise in a minority of states while declining or stabilising in most others. This variability highlights the unpredictable nature of the pandemic’s course and underlines the need for regionally tailored responses rather than uniform policies.

Experts emphasise that vaccines remain the cornerstone of managing COVID-19 despite fluctuating case numbers and evolving viral mutations. They also stress the importance of maintaining preventive measures such as mask-wearing in crowded settings, practising good hand hygiene and staying home when unwell to reduce transmission risk.

Malaysia’s experience demonstrates that containment is achievable with concerted public health efforts including transparent data reporting, genomic surveillance and targeted vaccination campaigns. The country’s avoidance of a recent surge experienced by its neighbours provides hope but also serves as a cautionary tale against complacency.

Continued monitoring of viral variants is essential to detect subtle shifts in transmissibility or symptomatology as they arise. The emergence of Nimbus exemplifies how new symptoms may appear with evolving strains without necessarily heralding more dangerous disease.

Individuals should stay informed through reliable official sources and adhere to recommended vaccinations and protective behaviours to safeguard themselves and their communities.

Malaysia’s relative success in maintaining control over COVID-19 amidst evolving variants like Nimbus underscores the value of vigilance, adaptability and science-driven public health strategies.

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Editorial Team
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